Endocrine Abstracts

Introduction and aim: The incidence of atherosclerotic vascular disease is high in obesity. Our aim is to determine the mean platelet volume (MPV) as a new indicator of atherosclerosis in morbid obesity.Materials and methods: Thirty-three patients with morbid obesity who applied to endocrinology department (mean age 41.5±11.3 years, body weight 118.2±16.9 kg and BMI: 45.9±7.2 kg/m2) and 39 age-matched (mean age 35.3±13.1 ye...

Aim: Mean platelet volume (MPV) is considered a new indicator of atherosclerosis. Activated platelets and subclinical inflammation predispose to create for atherosclerotic heart disease. Larger platelets are metabolically more active than smaller ones and have more protrombotic potential. We have recently demonstrated that MPV levels in Hashimoto’s patients tend to be higher than healthy controls even if in euthyroid state. In present study we aimed to investigate a relat...

Autoimmune polyendocrine syndromes (APS) are rare groups of diseases with autoimmune failure of at least two endocrine glands. In general, APS1 first occurs with candidiasis. Hypoparathyroidism generally presents until 10 years of age, and adrenal insufficiency around 20 years. We aim to this report a young girl is presented with early onset APS1 first presenting with adrenal insufficiency.Mucocutaneous candidiasis on the oral mucosa, and ectodermal dyst...

Sheehan’s syndrome (SS) may be defined as development of anterior pituitary ischemic necrosis, first of which is caused by failure to meet the blood build-up required due to pituitary expansion secondary to lactotroph cell proliferation during pregnancy. Vasospasm, thrombosis and vascular compression of hypophyseal arteries have been described among the possible causes of SS. Additionally, expansion of pituitary gland, small sella, disseminated intravascular coagulation (...

Aim: Isolated male hypogonadotropic hypogonadism can be congenital or acquired. Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for cardiovascular disease. The aim of this study is to evaluate MPV values in untreated, normosmic, isolated, male, idiopatic hypogonadotropic hypogonadism (IHH) patients, and the relationships among MPV, low testosterone levels, metabolic syndrome, impaired fasting glucose (IFG) and cardiovascul...

Pregnancy in active acromegaly at reproductive age is very rare occurrence due to hyperprolactinemia, hypogonadism and side effects of treatment of acromegaly. Only a few reports were described in medical literature by now.We report a 31-year-old woman ongoing active acromegaly despite who received Octeatide LAR 30 mg treatment monthly for the control of GH and IGF1 excess until realized her pregnancy. A GH secreting pituitary macroadenoma (tumor size 2 ...

Aim: Radioactive iodine (RAI) ablation therapy is used as part of the treatment for hyperthyroidism. Recently, low dose applied 131I treatment for hyperthyroidism has decreased the need for thyroidectomy. The aim of this study was to evaluate serum fasting glucose (FG) values in pre and post treatment RAI patients.Materials and Methods: Thirty-two patients with hyperthyroidism (mean age 56.0±14.5 years; range 24–83) treated with a si...

Introduction and objective: Recently, a lot of studies associated with high mean platelet level (MPV) in patients with hypo- and hyperthyroidism has reported in medical litherature. But it is not clear whether or not radioactive iodine treatment effect on platelet activity. It is well known that elevated platelet size is associated with its high enzymatic and metabolic activity. Aim of our preliminary study is to determine the platelet size via MPV level in hyperthyroid patien...

Introduction and aims: Mean platelet volume (MPV) is a newly indicator of platelet activation which was associated with atherosclerosis. There are limited studies in the literature about MPV levels in patients with both hypoparathyroidism and hyperparathyroidism. This preliminary study, we aimed to investigate a relationship with MPV and serum PTH and calcium levels in patients with disorder of calcium metabolism.Materials and methods: Fourty-nine hyperp...

Introduction: Hyperthyroidism is defined as thyroid hyperfunction due to overproduction of thyroid hormones. Graves disease is the most common cause of hyperthyroidism. Hyperthyroidism may be associated with glycemic dysregulation. We are presenting a case with diabetic ketoacidosis who had Graves disease and acute appendicitis.Case presentation: A nineteen years old female patient wtih Graves disease who had hyperthyroidism despite high dose antithyroid...